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Thermo Fisher Scientific CXCR1 Monoclonal Antibody (42705.111)
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Thermo Fisher Scientific CXCR1 Monoclonal Antibody (42705.111)

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인간 CXCR1 단백질을 인식하는 마우스 단클론 항체. IHC, Flow Cytometry, Neutralization 등 다양한 어플리케이션에 사용 가능. 비결합형 액상 형태로 제공되며, 낮은 엔도톡신 수준 보유. 연구용으로만 사용 가능.

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pk
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Thermo Fisher Scientific MA124668 CXCR1 Monoclonal Antibody (42705.111) 100 ug pk판매 단위 pk
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Thermo Fisher Scientific · Thermo Fisher Scientific CXCR1 Monoclonal Antibody (42705.111)

Applications and Tested Dilutions

Application Tested Dilution
Immunohistochemistry (Frozen) (IHC (F)) 25 µg/mL
Flow Cytometry (Flow) 10 µg/mL
Neutralization (Neu) Assay-dependent
Inhibition Assays (IA) 0.1–0.3 µg/mL

Product Specifications

Specification Description
Species Reactivity Human
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Clone 42705.111
Immunogen Human CXCR1 transfected NSO mouse myeloma cells
Conjugate Unconjugated
Form Liquid
Concentration 0.5 mg/mL
Purification Purified
Storage Buffer PBS with 5% trehalose
Contains No preservative
Storage Conditions Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping Conditions Ambient (domestic); Wet ice (international)
RRID AB_779600

Product Specific Information

  • Recommended positive control: human spleen
  • Human CXCR1 reacts with CXCR1 transfected cells and not with the parent cell line by flow cytometry.
  • The antibody shows no cross-reactivity with human CXCR2.
  • Endotoxin level is less than 10 ng per mg antibody as determined by the LAL method.

Target Information

CXCR1 is a member of the G-protein-coupled receptor family and serves as a receptor for interleukin 8 (IL8). It binds IL8 with high affinity and transduces signals via a G-protein–activated second messenger system. Knockout studies in mice suggest that CXCR1 inhibits embryonic oligodendrocyte precursor migration in the developing spinal cord. The IL8RB gene, encoding another high-affinity IL8 receptor, and IL8RBP, a pseudogene of IL8RB, form a gene cluster mapped to chromosome 2q33–q36.


For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.

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