Thermo Fisher Scientific Cripto Polyclonal Antibody
Cripto 단백질을 인식하는 Rabbit Polyclonal Antibody로 인간 및 생쥐 시료에 반응. Western blot, ICC/IF, Flow cytometry에 적합. 항원 친화 크로마토그래피로 정제된 액상 형태. 단기 4°C, 장기 -20°C 보관 권장.
- 카탈로그번호
- PA116534
- 판매단위
- pk
카탈로그
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 2 µg/mL | - |
| Immunocytochemistry (ICC/IF) | 1:1,000 | - |
| Flow Cytometry (Flow) | 1:100 | 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide made to an N-terminal portion of the murine cripto protein sequence (between residues 1–50). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_568503 |
Product Specific Information
In Western blot, a band is observed at approximately 18 kDa representing the core form of Cripto1, and at approximately 36 kDa representing the glycosylated/post-translationally modified form.
Suggested positive control: MDA-MB231 (human breast cancer) lysates.
Target Information
Cripto (TDGF1) is a GPI-anchored cell membrane protein involved in Nodal signaling.
Cell-associated TDGF1 acts as a Nodal coreceptor in cis.
Shedding of TDGF1 by TMEM8A modulates Nodal signaling by allowing soluble TDGF1 to act as a Nodal coreceptor on other cells.
TDGF1 is expressed in ES cells and during early phases of embryo development, and is reactivated in various epithelial cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA1-16534_Cripto_P51865-1_Rabbit.svg, PA1-16534_Cripto_P51865-1_Rabbit_PDP.jpeg)
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