Thermo Fisher Scientific RelB Monoclonal Antibody (F.576.6)
RelB 단백질을 인식하는 Rabbit monoclonal 항체로 Western blot 및 Immunoprecipitation에 사용 가능. Human, Mouse, Rat 등 다양한 종에 반응. Affinity chromatography로 정제된 액상형 항체이며, -20°C 보관. 연구용 전용 제품.
- 카탈로그번호
- MA514852
- 판매단위
- pk
카탈로그
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunoprecipitation (IP) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | F.576.6 |
| Immunogen | Synthetic peptide corresponding to residues surrounding Ser424 of human RelB protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 128 µg/mL |
| Purification | Affinity chromatography |
| Storage buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_10983755 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
The NFkB transcription factor was originally identified as a protein complex consisting of a DNA-binding subunit and an associated protein. The DNA-binding subunit is functionally related to c-Rel p75 and Rel B p68.
The p50 subunit was initially believed to be a functionally unique protein derived from the amino-terminus of a precursor designated p105. A second protein designated p52 (previously referred to as p49) has been identified that can act as an alternative NFkB subunit.
Rel B does not bind with high affinity to NFkB sites, but heterodimers between Rel B and p50 bind with an affinity comparable to that of p50 NFkB homodimers. However, Rel B/p50 heterodimers, in contrast to NFkB heterodimers, transactivate transcription of promoters containing kB binding sites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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