Thermo Fisher Scientific PUF60 Polyclonal Antibody
Thermo Fisher Scientific의 PUF60 Polyclonal Antibody는 Rabbit IgG 기반 액상 항체로 다양한 종에 반응 예측. WB, IHC, IP 등 다중 응용 가능하며, FFPE 조직에서 citrate buffer pH 6.0 처리 권장. 4°C 보관, 습식 얼음 배송.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:200–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 509 and 559 of Human Poly-U Binding Splicing Factor 60KDa |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
- Based on 100% sequence identity, this antibody is predicted to react with Rat, Bovine, and Orangutan
Target Information
PUF60 encodes a Ro RNP-binding protein that interacts with Ro RNPs, potentially conferring a gain of function. It forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein, represses a c-myc reporter via FUSE, and targets transcription factor IIH to inhibit activated transcription. This gene is implicated in xeroderma pigmentosum disorder. Two alternatively spliced transcript variants encode different isoforms, and multiple polyadenylation sites are suggested.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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