Thermo Fisher Scientific IL1F6 Polyclonal Antibody
IL1F6 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot에 적합하며, 고순도(>95%)로 정제됨. IL-36α 관련 염증성 사이토카인 연구에 활용 가능. 연구용으로만 사용.
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Thermo Fisher Scientific IL1F6 Polyclonal Antibody
Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein of human IL1F6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720082 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
The IL-1 family comprises 11 structurally related ligands, including IL-36α (IL-1F6), IL-36β (IL-1F8), and IL-36γ (IL-1F9).
IL-36α is highly expressed in psoriatic plaques and uniquely expressed by T cells, monocytes, and B cells. It is primarily found in skin and lymphoid tissues, and to a lesser extent in fetal brain, trachea, stomach, and intestine.
IL-36α signals through IL-1Rrp2 (IL-1R6) and IL-RAcP receptors, functioning as an agonist of NF-κB and MAPK pathways. It induces proinflammatory cytokines and chemokines such as IL-6, IL-8, BD-2, and BD-3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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