Thermo Fisher Scientific Phospho-HDAC5/HDAC9 (Ser259, Ser220) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (IHC)

1:100-1:300

-

ELISA (ELISA)

1:10,000

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthesized peptide derived from human HDAC5/9 around the phosphorylation site of S259/220. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:HDAC5/HDAC9,uniProtId:Q9UKV0-1,ncbiNodeId:9606,antigenRange:220,antigenLength:1011,antigenImageFileName:PA5-40215_HDAC5HDAC9_Q9UKV0-1_Rabbit.svg,antigenImageFileNamePDP:PA5-40215_HDAC5HDAC9_Q9UKV0-1_Rabbit_PDP.jpeg,sortOrder:1},{targetFamily:HDAC5/HDAC9,uniProtId:Q9UQL6-1,ncbiNodeId:9606,antigenRange:259,antigenLength:1122,antigenImageFileName:PA5-40215_HDAC5HDAC9_Q9UQL6-1_Rabbit.svg,antigenImageFileNamePDP:PA5-40215_HDAC5HDAC9_Q9UQL6-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol, 0.5% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2576598

Product Specific Information

This antibody is predicted to react with mouse based on sequence homology.

Target Information

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.