Thermo Fisher Scientific Phospho-SHB (Tyr246) Polyclonal Antibody
인간 및 생쥐에서 반응하는 Phospho-SHB (Tyr246) 폴리클로날 항체로, Western blot 및 ELISA에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 버퍼에 보관됩니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human Shb around the phosphorylation site of Y246 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.5% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2607756 |
Product Specific Information
This antibody is predicted to react with mouse based on sequence homology.
Target Information
The SH2 (Src Homology 2) domain is a structurally conserved motif containing two alpha helices and seven beta strands, found in proteins involved in cellular signal transduction. The SH2 domain binds to tyrosine-phosphorylated sites, initiating protein-protein interaction cascades that can influence gene expression and cellular function.
Shb (SH2 domain-containing adapter protein b), Shd, She, and Shf are SH2 domain-containing proteins with distinct roles in cellular signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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