Thermo Fisher Scientific Activin A Polyclonal Antibody
Activin A 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체. 인간, 마우스, 랫트 반응성. Western blot에 적합하며 고순도(>95%) 항원 친화 크로마토그래피 정제. 장기 보관 시 -20°C에서 보관 권장.
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Thermo Fisher Scientific Activin A Polyclonal Antibody
Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to residues in Human Inhibin beta-A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803546 |
Product Specific Information
Purity is >95% by SDS-PAGE.
Target Information
Activins are dimeric growth and differentiation factors belonging to the transforming growth factor-beta (TGF-beta) superfamily. They signal through a heteromeric complex of receptor serine kinases, including type I (I and IB) and type II (II and IIB) receptors. These receptors are transmembrane proteins consisting of a ligand-binding extracellular domain, a transmembrane domain, and a cytoplasmic domain with serine/threonine kinase activity. Type I receptors are essential for signaling, while type II receptors are required for ligand binding and type I receptor expression. Upon ligand binding, type I and II receptors form a stable complex, leading to phosphorylation of type I receptors by type II receptors. Activin A mutations are associated with fibrodysplasia ossificans progressiva.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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