Thermo Fisher Scientific CD105 Monoclonal Antibody (3A9)
인간 CD105 단백질을 검출하는 마우스 모노클로날 항체로, WB, IHC, ICC/IF, Flow Cytometry, ELISA 등 다양한 응용에 적합합니다. 비결합(Unconjugated) 형태이며, 4°C 또는 -20°C에서 안정적으로 보관 가능합니다. 연구용으로만 사용됩니다.
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- MA517041
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Thermo Fisher Scientific CD105 Monoclonal Antibody (3A9)
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | - |
| Immunohistochemistry (IHC) | - | 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 | 1 publication |
| Flow Cytometry (Flow) | 1:200–1:400 | 1 publication |
| ELISA | 1:10,000 | - |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3A9 |
| Immunogen | Purified recombinant fragment of human CD105 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Ascites |
| Contains | 0.03% Sodium Azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet Ice |
| RRID | AB_2538513 |
Product Specific Information
MA5-17041 targets CD105 in indirect ELISA, FACS, ICC, IF, IHC, and WB applications and shows reactivity with human samples.
The MA5-17041 immunogen is a purified recombinant fragment of human CD105 expressed in E. coli.
MA5-17041 detects CD105 with a predicted molecular weight of approximately 71 kDa.
Target Information
CD105 (Endoglin) is a Type I transmembrane protein highly expressed on human vascular endothelial cells. It exists as an O- and N-glycosylated homodimer.
Upregulation of endoglin expression has been observed in tumor vasculature and proliferating cells, indicating its role as a proliferation-associated endothelial marker.
CD105 binds TGF-β1 and TGF-β3 with high affinity but not TGF-β2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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