
Thermo Fisher Scientific ASCC2 Monoclonal Antibody (OTI1E8), TrueMAB
ASCC2 단백질을 인식하는 Mouse IgG1 단일클론 항체로 인간 시료에 반응합니다. Western blot, ICC/IF, Flow cytometry에 사용 가능하며, DNA 손상 복구 관련 연구에 적합합니다. Lyophilized 형태로 제공되며 PBS buffer에 보관합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E8 |
| Immunogen | Full length human recombinant protein of human ASCC2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
ASCC2 plays a role in DNA damage repair as a component of the ASCC complex. It recruits ASCC3 and ALKBH3 to DNA damage sites by binding to polyubiquitinated proteins with Lys-63-linked polyubiquitin chains (PubMed:29144457).
Part of the ASC-1 complex that enhances NF-kappa-B, SRF, and AP1 transactivation (PubMed:12077347). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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