Thermo Fisher Scientific FGFR2 Monoclonal Antibody (OTI1A11), TrueMAB
FGFR2 단백질을 인식하는 Mouse IgG2a 단일클론 항체로 Western blot에 최적화됨. 인간 시료 반응성, 무보존제, 동결건조 형태. 재구성 및 결합 실험에 적합하며, 세포 성장 및 분화 연구용으로 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1A11 |
| Immunogen | Full-length human recombinant FGFR2 protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
FGFR2 (Fibroblast Growth Factor Receptor 2) is a receptor tyrosine kinase involved in various cellular processes such as angiogenesis, mitogenesis, osteogenesis, myogenesis, carcinogenesis, cellular differentiation, and tissue repair.
Mutations in FGFR2 are associated with numerous syndromes, including Crouzon, Pfeiffer, Apert, Jackson-Weiss, Beare-Stevenson cutis gyrata, Saethre-Chotzen, and syndromic craniosynostosis.
Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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