
Thermo Fisher Scientific CDKN2C Monoclonal Antibody (OTI1C12), TrueMAB
CDKN2C 단백질을 인식하는 마우스 모노클로날 항체로, Western blot에 적합합니다. 인간 시료에 반응하며, 고순도 친화 크로마토그래피로 정제되었습니다. 안정한 액상 형태로, PBS/BSA/glycerol 완충액에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C12 |
| Immunogen | Full length human recombinant protein of human CDKN2C produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. It interacts with CDK4 or CDK6 and prevents activation of CDK kinases, functioning as a regulator of cell cycle G1 progression. Ectopic expression suppresses human cell growth in correlation with wild-type RB1 function. Knockout mouse studies suggest roles in spermatogenesis regulation and tumorigenesis suppression. Two alternatively spliced transcript variants encoding the same protein have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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