Thermo Fisher Scientific CDKN2C Monoclonal Antibody (OTI6B3), TrueMAB
CDKN2C 단백질을 인식하는 마우스 단클론 항체로, Western blot에 최적화되어 있습니다. 인간 시료에 반응하며, 세포 주기 조절 연구에 유용합니다. 고순도 친화 크로마토그래피 정제 제품으로 안정적인 액상 형태로 제공됩니다.
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Applications
- Western Blot (WB): 1:2,000 희석 비율로 테스트됨
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6B3 |
| Immunogen | Full length human recombinant protein of human CDKN2C produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. It interacts with CDK4 or CDK6 to prevent activation of CDK kinases, functioning as a regulator of cell cycle G1 progression. Ectopic expression can suppress human cell growth in correlation with wild-type RB1 function. Knockout mouse studies suggest roles in spermatogenesis regulation and tumor suppression. Two alternatively spliced transcript variants encoding an identical protein have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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