Thermo Fisher Scientific CDKN2C Monoclonal Antibody (OTI2E1), TrueMAB
CDKN2C 단백질을 인식하는 Mouse monoclonal antibody로 Western blot에 최적화되어 있습니다. Human 시료에 반응하며, Affinity chromatography로 정제되었습니다. PBS/BSA/glycerol buffer에 보관되며, 연구용으로만 사용 가능합니다.
- 카탈로그번호
- TA801184
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 1:2,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2E1 |
| Immunogen | Full length human recombinant protein of human CDKN2C produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. It interacts with CDK4 or CDK6, preventing activation of CDK kinases and regulating cell cycle G1 progression. Ectopic expression suppresses human cell growth in correlation with wild-type RB1 function. Knockout mouse studies suggest roles in spermatogenesis regulation and tumorigenesis suppression. Two alternatively spliced transcript variants encoding an identical protein have been reported.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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