Thermo Fisher Scientific PDE8A Polyclonal Antibody, FITC
PDE8A 단백질을 인식하는 FITC 표지 폴리클로날 항체로, Western blot, IHC, ICC/IF, ELISA 등 다양한 응용에 적합합니다. Human, Mouse, Rat 등 반응성이 있으며, 형광 검출(Ex/Em 498/517 nm)에 최적화되어 있습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| Immunocytochemistry (ICC/IF) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
| Immunomicroscopy (IM) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic cyclic peptide from mid-region common to all PDE8A variants |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Phosphodiesterases (PDEs) regulate intracellular levels of cAMP and cGMP, which act as second messengers in various physiological processes such as vascular resistance, cardiac output, visceral motility, immune response, inflammation, neuroplasticity, vision, and reproduction. PDEs form a large superfamily divided into 10 families, distinguishable by structure, tissue expression, localization, substrate specificity, regulation, and sensitivity to inhibitors. Their diversity makes PDEs promising targets for pharmacotherapy of diseases modulated by cyclic nucleotide signaling (Hetman et al., 2000).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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