Thermo Fisher Scientific PDE8A Polyclonal Antibody, FITC
FITC로 결합된 PDE8A 폴리클로날 항체로, 인간 및 설치류 등 다양한 종에 반응. WB, IHC, ICC, ELISA 등 다중 응용 가능. 고순도 친화 크로마토그래피 정제. 연구용으로만 사용, -20°C 암소 보관.
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Thermo Fisher Scientific PDE8A Polyclonal Antibody, FITC
Applications 및 권장 희석 배율
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| Immunocytochemistry (ICC/IF) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
| Immunomicroscopy (IM) | 1:50–1:200 |
제품 사양
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic cyclic peptide from C terminus common to all PDE8A variants |
| Conjugate | FITC (Fluorescein) |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Phosphodiesterases (PDEs) regulate intracellular levels of cAMP and cGMP, which act as second messengers in various physiological processes such as vascular resistance, cardiac output, visceral motility, immune response, inflammation, neuroplasticity, vision, and reproduction. PDEs are a large enzyme superfamily divided into 10 families, each distinguished by structure, tissue expression, localization, substrate specificity, regulation, and inhibitor sensitivity. Their diversity makes PDEs promising targets for pharmacotherapy of diseases modulated by cyclic nucleotide signaling (Hetman et al., 2000).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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