Thermo Fisher Scientific PDE8A Polyclonal Antibody, FITC
FITC로 결합된 PDE8A 폴리클로날 항체로 다양한 종에서 반응하며 WB, IHC, ICC, ELISA 등 다중 응용 가능. 높은 특이성과 감도를 제공하며 세포 내 cAMP/cGMP 조절 연구에 적합. 액상 형태로 -20°C 암소 보관.
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Thermo Fisher Scientific PDE8A Polyclonal Antibody, FITC
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| Immunocytochemistry (ICC/IF) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
| Immunomicroscopy (IM) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Bovine, Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic cyclic peptide from near the N terminus common to all PDE8A variants |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Phosphodiesterases (PDEs) regulate intracellular levels of cAMP and cGMP, which act as second messengers in various physiological processes such as vascular resistance, cardiac output, visceral motility, immune response, inflammation, neuroplasticity, vision, and reproduction. PDEs form a large enzyme superfamily divided into 10 families, distinguished by structure, tissue expression, localization, substrate specificity, regulation, and sensitivity to inhibitors. Their diversity makes PDEs promising pharmacological targets for diseases modulated by cyclic nucleotide signaling (Hetman et al., 2000).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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