Thermo Fisher Scientific HIV1 Protease Monoclonal Antibody (1696)
HIV-1 및 HIV-2 프로테아제의 성숙 단백질 N-말단을 인식하는 단클론 항체. Western blot, ELISA, 기능적 분석에 사용 가능. 단백질 A로 정제된 마우스 IgG1 항체로 1 mg/mL 농도. 4°C 보관, 동결 금지.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.5 µg/mL | View 1 publication |
| ELISA | Assay-dependent | - |
| Functional Assay | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Virus |
| Published Species | Virus |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1696 |
| Immunogen | Bacterially expressed full-length HIV-1 protease |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1075640 |
Product Specific Information
This antibody recognizes the free N-terminus of mature HIV protease (HIV-1 and HIV-2), an enzyme that hydrolyzes polyproteins of HIV viruses into functional proteins. The antibody 1696 does not react with the precursor.
Functional Application: Inhibition.
Target Information
A protease is an enzyme that cleaves proteins into their component peptides. The HIV protease (PR) hydrolyzes viral polyproteins into functional protein products essential for viral assembly and activity. This maturation process occurs as the virion buds from the host cell. HIV protease inhibitors are used in AIDS treatment and represented a major breakthrough in antiviral therapy, effectively reducing viral load in patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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