Thermo Fisher Scientific GTF3C4 Monoclonal Antibody (OTI4H1), TrueMAB
GTF3C4 단백질을 인식하는 단클론 항체로, Western blot에 최적화되어 있습니다. Human, Mouse, Rat에서 반응하며, IgG2a 동종형을 가집니다. 동결건조 형태로 제공되며, 재구성 후 약 1 mg/mL 농도로 사용 가능합니다. RNA polymerase III 관련 연구에 적합합니다.
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Applications
- Western Blot (WB): 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4H1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 583–822 of human GTF3C4 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional round of desalting (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
GTF3C4 is essential for RNA polymerase III to synthesize small nuclear and cytoplasmic RNAs, including 5S RNA, tRNA, and adenovirus-associated (VA) RNA.
It possesses histone acetyltransferase (HAT) activity with specificity for free and nucleosomal H3.
May cooperate with GTF3C5 to facilitate recruitment of TFIIIB and RNA polymerase through interactions with BRF1, POLR3C, and POLR3F.
[UniProt: Q9UKN8]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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