Thermo Fisher Scientific GTF3C4 Monoclonal Antibody (OTI3D4), TrueMAB
GTF3C4 단백질을 인식하는 Mouse IgG1 단클론 항체로, WB 및 IHC(P) 실험에 적합. 인간, 마우스, 원숭이, 랫트 반응성. 동결건조 형태로 제공되며 PBS 버퍼(8% trehalose) 포함. RNA polymerase III 관련 연구용.
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Thermo Fisher Scientific GTF3C4 Monoclonal Antibody (OTI3D4), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3D4 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 583–822 of human GTF3C4 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
GTF3C4 is essential for RNA polymerase III to synthesize small nuclear and cytoplasmic RNAs such as 5S RNA, tRNA, and adenovirus-associated (VA) RNA.
It exhibits histone acetyltransferase (HAT) activity with specificity for free and nucleosomal H3.
May cooperate with GTF3C5 in recruiting TFIIIB and RNA polymerase via interactions with BRF1, POLR3C, and POLR3F.
May be localized near the A box. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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