Thermo Fisher Scientific ErbB2 (HER-2) Recombinant Mouse Monoclonal Antibody (FWP51)
ErbB2(HER2) 단백질을 인식하는 마우스 유래 재조합 단클론 항체입니다. ICC/IF, Flow Cytometry, IP 등 다양한 응용에 사용 가능합니다. 인간 시료에 반응하며, Protein A로 정제된 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| Flow Cytometry (Flow) | 1:100 |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | FWP51 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3074632 |
Immunogen
20×10^6 SKBR3 human breast tumour cells were injected into BALB/c mice. The hybridomas generated from the mice spleen cells were then screened for antibodies reactive to c-erbB-2 using immunofluorescence and immunoprecipitation.
Target Family: Her-2 (ErbB2)
UniProt ID: P04626-1
Antigen Range: 1–1255 (length 1255 aa)
Product Specific Information
Specificity: FWP51 binds to the extracellular domain of c-erbB-2.
Target Information
ErbB2 (HER2) is a receptor tyrosine kinase that is overexpressed in some breast tumors. Herceptin, used in treatment of metastatic Her2-positive cancer, is a monoclonal antibody targeting this kinase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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