Thermo Fisher Scientific RHD Chimeric Recombinant Rabbit Monoclonal Antibody (D7C2)
RHD 단백질을 표적으로 하는 재조합 키메릭 토끼 단클론 항체로, 인간 시료에 반응합니다. ICC/IF, 유세포분석, 세포독성 분석에 사용 가능하며, 고순도의 Protein A 정제 항체입니다. 연구용으로만 사용되며, 장기 보관 시 -20°C에서 안정적입니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| Flow Cytometry (Flow) | 1:100 |
| Cytotoxicity Assay (CT) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG, lambda |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | D7C2 |
| Immunogen | A Rh- volunteer blood donor (r/r) was injected with 5 ml of Rh+ erythrocytes (R1/r). Peripheral lymphocytes were isolated and transformed with 1 ml of culture supernatant of the EBV marmoset B96-8 cell line. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_3074631 |
Target Information
The Rhesus (Rh) blood group system represents one of the most complex and important systems in humans. Two highly homologous genes RHD and RHCE (collectively referred to as RH30 or RHCED) encode the antigens of the Rh blood group system. These genes map to human chromosomal position 1p34.1–1p36.
The RHD gene encodes the D antigen, the most potent blood group immunogen. Rh incompatibility between maternal and fetal blood types can result in hemolytic disease of the newborn (HDN). The RHCE gene exists in four allelic forms, each determining the expression of Ce, ce, cE, or CE antigen combinations. RHCED antigens are integral membrane proteins with 12 transmembrane helices, contributing to erythrocyte membrane integrity. Presentation of Rh antigenic activity requires complex formation between RHCED antigens and RHAG (RH50).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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