Thermo Fisher Scientific Phospho-c-Jun (Thr239) Polyclonal Antibody
인간 및 생쥐 반응성의 phospho-c-Jun (Thr239) 폴리클로날 항체로, WB 및 IHC(P) 분석에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 0.5 mg/mL 농도의 액상 형태로 제공됩니다. UV 처리된 HeLa 세포를 양성 대조로 사용하며, 핵 내 위치 단백질 검출에 유용합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.1–1 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the epitope -GETPP- at phosphorylation site Thr239 of human c-Jun protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 25 mM Tris with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: UV-treated HeLa cells
- Cellular location: Nucleus
Target Information
c-Jun is a transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'.
It promotes activity of NR5A1 when phosphorylated by HIPK3, leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.
Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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