Thermo Fisher Scientific Human Grik2 Synthetic Peptide
Human Grik2 단백질의 C-말단 13개 아미노산 서열에 해당하는 합성 펩타이드로, PA5-20449 항체의 블로킹 펩타이드로 사용 가능. 인간 시료에 반응하며, PBS(pH 7.2)와 0.1% BSA, 0.02% sodium azide를 포함. 연구용으로만 사용.
- 카탈로그번호
- PEP0566
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 13 amino acids near the carboxy terminus of human Grik2.
PEP-0566 can be used as a blocking peptide with polyclonal antibody PA5-20449.
Target Information
Glutamate receptors are the primary excitatory neurotransmitter receptors in the mammalian brain and are activated during various normal neurophysiological processes. The kainate family of glutamate receptors, composed of four subunits functioning as ligand-activated ion channels, includes this gene product.
The subunit encoded by this gene is edited at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Different isoforms of this gene have been described due to alternatively spliced transcript variants.
Mutations in this gene have been linked to autosomal recessive cognitive disability. GRIK2-associated diseases include Neurodevelopmental Disorder with Impaired Language and Ataxia, and Intellectual Developmental Disorder, Autosomal Recessive 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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