Thermo Fisher Scientific Human GRIK5 Synthetic Peptide
인간 GRIK5 단백질의 C-말단 부근 17개 아미노산 서열을 기반으로 한 합성 펩타이드. 항체 PA5-20451의 블로킹 펩타이드로 사용 가능. 정제된 액상 형태로 PBS 완충액에 보관. 연구용으로만 사용.
- 판매단위
- pk
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
Product Specific Information
This peptide corresponds to 17 amino acids near the carboxy terminus of human Grik5.
PEP-0568 can be used as a blocking peptide with polyclonal antibody PA5-20451.
Target Information
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes.
Grik5, also known as kainate-preferring glutamate receptor subunit KA2, belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels.
Grik5 is highly homologous to the related ionotropic glutamate receptor Grik4 (also known as KA1). Like Grik4, Grik5 does not form homomeric channels but instead forms heteromers with Grik2.
In Grik2- but not Grik1- mice, Grik5 surface expression is greatly reduced in neurons, indicating that Grik2/Grik5 heteromers are required for exit from the endoplasmic reticulum to the cell surface.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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