Thermo Fisher Scientific NR0B2 Monoclonal Antibody (OTI8E5), TrueMAB
NR0B2 단백질을 표적으로 하는 마우스 단클론 항체로, Western blot과 IHC(파라핀) 분석에 적합합니다. 고순도의 친화 크로마토그래피 정제 제품이며, 보존제가 없는 PBS 버퍼에 동결건조 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific NR0B2 Monoclonal Antibody (OTI8E5), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-Dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8E5 |
| Immunogen | Full length human recombinant protein of human NR0B2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The NR0B2 gene encodes an orphan nuclear receptor lacking a conventional DNA-binding domain but containing a ligand-binding domain. It interacts with retinoid, thyroid, and estrogen receptors, inhibiting their ligand-dependent transcriptional activation. The protein represses nuclear hormone receptor-mediated transactivation through competition with coactivators and direct transcriptional repression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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