Thermo Fisher Scientific CSNK1G1 Monoclonal Antibody (OTI1D7), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:150

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

Casein kinase I (CKI) and casein kinase II (CKII) compose a family of serine/threonine protein kinases present in all eukaryotes.
CKI family members (α, γ, ε, δ) are involved in cytoplasmic and nuclear processes such as DNA replication and repair.
CKII exists as a tetrameric complex (α2β2 or αα′β2), where the β subunit regulates and autophosphorylates the α catalytic subunit.
CKII activity is high in proliferating and differentiating cells and phosphorylates over 100 substrates, including nuclear oncoproteins, transcription factors, and DNA metabolism enzymes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.