Thermo Fisher Scientific Phospho-YBX1 (Ser102) Polyclonal Antibody
YBX1 단백질의 Ser102 인산화 형태를 특이적으로 인식하는 폴리클로날 항체입니다. Western blot에 최적화되어 있으며 HepG2 세포에서 양성 대조로 사용됩니다. 세포질 및 핵 내 YBX1 검출에 적합하며 연구용으로만 사용됩니다.
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Thermo Fisher Scientific Phospho-YBX1 (Ser102) Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:500 – 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphorylated peptide around S102 of human YB-1/YBX1 (NP_004550.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.97 mg/mL |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914926 |
Product Specific Information
- Positive test controls include: HepG2
- Target localization: Cytoplasm, Cytoplasmic granule, Nucleus, Secreted
Target Information
YBX1 binds to splice sites in pre-mRNA and regulates splice site selection. It stabilizes cytoplasmic mRNA and modulates translation by interacting with eukaryotic initiation factors. YBX1 also binds to promoters containing a Y-box sequence (5'-CTGATTGGCCAA-3'), such as HLA class II genes, and regulates transcription. It promotes DNA strand separation in mismatched or cisplatin-modified DNA, exhibits endonucleolytic activity, and may play a role in DNA repair.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-121354_YBX1_P67809-1_Rabbit.svg, PA5-121354_YBX1_P67809-1_Rabbit_PDP.jpeg)
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