
Thermo Fisher Scientific TYRP1 Chimeric Recombinant Rabbit Monoclonal Antibody (TA99)
TYRP1 단백질을 인식하는 재조합 토끼 단클론 항체로 멜라닌 생합성 연구에 적합. Western blot, IHC, ICC, Flow cytometry, ELISA, IP 등 다양한 응용 가능. HEK293 발현, Protein A 정제, 1 mg/mL 농도, PBS 버퍼에 ProClin 300 포함.
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Thermo Fisher Scientific TYRP1 Chimeric Recombinant Rabbit Monoclonal Antibody (TA99)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
| Flow Cytometry (Flow) | Assay-dependent |
| ELISA | Assay-dependent |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | TA99 |
| Immunogen | 70–75 kDa pigmentation-associated glycoprotein in human melanoma cell lines |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3074274 |
Product Specific Information
Specificity: Binds Tyrosinase-related protein-1 (TRP-1), a 70–75 kDa enzyme located in melanocytes. TRP-1 stabilizes tyrosinase, the enzyme responsible for the first step in melanin production, and determines the shape of melanosomes, the structures where melanin is produced.
Target Information
This gene encodes a melanosomal enzyme belonging to the tyrosinase family. It plays an essential role in the melanin biosynthetic pathway. Defects in this gene cause rufous oculocutaneous albinism and oculocutaneous albinism type III.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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