Thermo Fisher Scientific CD4 Monoclonal Antibody (OTI4F10), TrueMAB
인간 CD4 단백질을 인식하는 단클론 항체로, Western blot에 최적화되어 있습니다. TrueMAB 형식의 Mouse IgG2b 항체이며, 고순도 친화 크로마토그래피 정제 제품입니다. PBS/BSA/glycerol 버퍼에 보관되며 -20°C에서 안정적으로 저장 가능합니다.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4F10 |
| Immunogen | Full length human recombinant protein of human CD4 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The CD4 antigen is involved in the recognition of MHC class II molecules and acts as a co-receptor for HIV. CD4 is primarily expressed on T helper cells but may also be found on monocytes, macrophages, and dendritic cells. It is detected in thymus, lymph nodes, tonsils, spleen, and certain non-lymphoid tissues such as brain and gut. CD4 contributes to T-cell activation by associating with the T-cell receptor complex and protein tyrosine kinase Lck. It may also play a role in neuronal damage in infectious and immune-mediated CNS diseases. Multiple alternatively spliced transcripts have been identified (RefSeq, July 2017).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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