Thermo Fisher Scientific CD4 Monoclonal Antibody (OTI2D1), TrueMAB

Applications and Tested Dilution

Product Specifications

Target Information

The CD4 antigen is involved in the recognition of MHC class II molecules and acts as a co-receptor for HIV. CD4 is primarily expressed in a subset of T-lymphocytes (T helper cells) and may also be found in monocytes, macrophages, and dendritic cells.
At the tissue level, CD4 expression is detected in thymus, lymph nodes, tonsils, spleen, and in specific regions of the brain, gut, and other non-lymphoid tissues.
CD4 functions to initiate or augment early T-cell activation via association with the T-cell receptor complex and protein tyrosine kinase Lck. It may also mediate direct neuronal damage in infectious and immune-mediated diseases of the central nervous system.
Multiple alternatively spliced transcripts have been identified for this gene (RefSeq, July 2017).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.