Thermo Fisher Scientific CD4 Monoclonal Antibody (OTI2D1), TrueMAB
CD4 단백질을 인식하는 마우스 모노클로날 항체. Western blot 및 IHC(P) 실험에 적합. 인간 시료 반응성. 1 mg/mL 농도의 액상 제품으로, PBS/BSA/glycerol 완충액에 보존. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D1 |
| Immunogen | Full length human recombinant protein of human CD4 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The CD4 antigen is involved in the recognition of MHC class II molecules and acts as a co-receptor for HIV. CD4 is primarily expressed in a subset of T-lymphocytes (T helper cells) and may also be found in monocytes, macrophages, and dendritic cells.
At the tissue level, CD4 expression is detected in thymus, lymph nodes, tonsils, spleen, and in specific regions of the brain, gut, and other non-lymphoid tissues.
CD4 functions to initiate or augment early T-cell activation via association with the T-cell receptor complex and protein tyrosine kinase Lck. It may also mediate direct neuronal damage in infectious and immune-mediated diseases of the central nervous system.
Multiple alternatively spliced transcripts have been identified for this gene (RefSeq, July 2017).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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