Thermo Fisher Scientific Protein C Polyclonal Antibody
Human Protein C를 인식하는 sheep polyclonal antibody로, Western blot 및 ELISA에 적합. 비결합형 액상 형태이며, 고농도(8.6 mg/mL)로 제공. SDS-PAGE로 정제되어 있으며, -20°C에서 보관 권장. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 25 µg/mL |
| ELISA | 5–10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Human Protein C |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 8.6 mg/mL |
| Purification | SDS-PAGE |
| Storage Buffer | 50% water with 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1086889 |
Product Specific Information
PA1-43051 detects Protein C in human samples.
It has been successfully used in Western blot and ELISA applications.
PA1-43051 was derived from human Protein C.
Target Information
Protein C is a vitamin K-dependent plasma glycoprotein that is cleaved to its activated form by the thrombin-thrombomodulin complex.
Activated Protein C contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII.
It is produced in the liver and composed of two polypeptide chains.
The 62 kDa proenzyme is activated by thrombin bound to an endothelial surface receptor, and the active enzyme (55 kDa) cleaves factor Va and VIIIa, thereby inhibiting blood coagulation.
Normal plasma concentrations are approximately 1–3 ng/mL for the active enzyme and 3 µg/mL for the proenzyme.
Mutations in the Protein C gene are associated with thrombophilia due to Protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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