Thermo Fisher Scientific Factor XII Polyclonal Antibody
Human Factor XII에 특이적인 Sheep Polyclonal Antibody로 Western blot 및 ELISA에 사용 가능. 고농도(8.4 mg/mL) 액상 형태로 제공되며, SDS-PAGE로 정제됨. -20°C에서 보관하며 동결·해동 반복은 피해야 함.
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Thermo Fisher Scientific Factor XII Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 5–10 µg/mL |
| ELISA | 5–10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Human Factor XII |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 8.4 mg/mL |
| Purification | SDS-PAGE |
| Storage Buffer | 50% water with 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1074351 |
Product Specific Information
PA1-43049 detects Factor XII in human samples.
It has been successfully used in Western blot and ELISA applications.
PA1-43049 was derived from human Factor XII.
Target Information
Factor XII is a single-chain zymogen that is converted to a two-chain serine protease consisting of a heavy chain (alpha-factor XIIa) and a light chain.
The heavy chain contains fibronectin-type domains, EGF-like domains, a kringle domain, and a proline-rich domain, while the light chain contains only a catalytic domain.
Upon activation, further cleavage produces beta-factor XIIa.
Factor XII plays a key role in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin.
It activates coagulation factors VII and XI.
Defects in this gene prolong whole-blood clotting time but do not cause clinical symptoms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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