Thermo Fisher Scientific SERPINC1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

25 µg/mL

-

ELISA (ELISA)

5-10 µg/mL

-

Inhibition Assays (IA)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Sheep / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Human Antithrombin III.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

14.4 mg/mL

Purification

SDS-PAGE

Storage buffer

50% water with 50% glycerol

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2186619

Product Specific Information

PA1-43054 detects SERPINC1 in human samples.

PA1-43054 has successfully been used in Western blot and ELISA applications.

PA1-43054 was derived from human antithrombin III.

Target Information

The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.