Thermo Fisher Scientific Follicular Dendritic Cells Monoclonal Antibody (ED5)
Follicular Dendritic Cells를 검출하기 위한 ED5 클론의 Mouse Monoclonal Antibody. Frozen tissue IHC에 적합하며 Rat spleen cells로부터 유래. Unconjugated 형태로 제공되며 1 mg/mL 농도, 4°C 단기 및 -20°C 장기 보관 가능.
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Thermo Fisher Scientific Follicular Dendritic Cells Monoclonal Antibody (ED5)
Applications
- Immunohistochemistry (Frozen) (IHC (F))
Tested Dilution: 1:100–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | ED5 |
| Immunogen | Rat spleen cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2538157 |
Product Specific Information
This antibody does not react with mouse.
Target Information
Follicular Dendritic Cells (FDCs) are large cells located in germinal centers (GCs) of primary and lymphoid tissues. They present non-processed antigens and inhibit apoptosis of B cells through selection processes that result in memory B cell formation.
FDCs express several B cell markers, including CD21 (long isoform), CD23, and CD35.
A role for FDCs has been demonstrated in various infectious diseases such as AIDS and transmissible spongiform encephalitis.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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