Thermo Fisher Scientific TPSB2 Monoclonal Antibody (349406)
Human TPSB2 단백질을 인식하는 mouse monoclonal antibody. Western blot 및 Immunoprecipitation에 검증됨. Lyophilized 형태로 제공되며 Protein A/G로 정제. PBS 및 trehalose buffer에 보관, 연구용으로 적합.
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Thermo Fisher Scientific TPSB2 Monoclonal Antibody (Clone 349406)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunoprecipitation (IP) | 25 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 349406 |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human Tryptase beta-2/TPSB2 (Ile31–Pro275) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2609249 |
Product Specific Information
- In direct ELISAs and Western blots, 50–100% cross-reactivity with recombinant human TPSAB1 and recombinant mouse Mcpt6 is observed.
- 20–100% cross-reactivity with recombinant mouse Mcpt7 is observed.
- No cross-reactivity with recombinant human TPSG1, mouse TPS5, Mcpt1, or Mcpt11.
- Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
TPSB2 is a protein coding gene belonging to the tryptase family of serine proteases (peptidase family S1).
Tryptases are active only as heparin-stabilized tetramers and resistant to endogenous proteinase inhibitors.
These genes cluster on chromosome 16p13.3 and share conserved 3′ UTRs with tandem repeats regulating mRNA stability.
Distinct allelic variations exist, historically classified as beta II and beta III.
Beta tryptases are primarily expressed in mast cells, while alpha tryptases dominate in basophils.
Tryptases are implicated in asthma and allergic or inflammatory disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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