Thermo Fisher Scientific TPSB2 Monoclonal Antibody (349414)
인간 TPSB2 단백질을 인식하는 Mouse IgG1 단일클론 항체로 Western blot, Immunoprecipitation, Neutralization 실험에 적합. Protein A/G로 정제되어 PBS + trehalose에 보관. 교차반응 없음, 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunoprecipitation (IP) | 25 µg/mL |
| Neutralization (Neu) | 1.4 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 349414 |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human Tryptase beta-2/TPSB2 (Ile31–Pro275) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2609250 |
Product Specific Information
- In direct ELISAs and Western blots, no cross-reactivity with recombinant human TPS1, TPSG1, recombinant mouse TPS5, MCPT1, MCPT6, MCPT7, or MCPT11 is observed.
- Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
TPSB2 is a protein coding gene. Tryptases comprise a family of trypsin-like serine proteases (peptidase family S1). They are enzymatically active only as heparin-stabilized tetramers and resistant to all known endogenous proteinase inhibitors.
Several tryptase genes are clustered on chromosome 16p13.3 and exhibit high sequence conservation and tandem repeat sequences at the 5′ and 3′ UTR regions, contributing to mRNA stability regulation.
Beta tryptases are mainly expressed in mast cells, while alpha tryptases predominate in basophils. Tryptases are implicated in asthma and other allergic and inflammatory disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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