Thermo Fisher Scientific Relaxin 2 Monoclonal Antibody (349102)

Applications

Tested Dilution

Publications

Western Blot (WB)

2 µg/mL

-

Neutralization (Neu)

1.5-6.0 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rat / IgG1

Class

Monoclonal

Type

Antibody

Clone

349102

Immunogen

E. coli-derived recombinant human Relaxin-2 Val23-Cys185 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Relaxin 2,uniProtId:P04090-1,ncbiNodeId:9606,antigenRange:23-185,antigenLength:185,antigenImageFileName:MA5-24088_Relaxin_2_P04090-1_Rat.svg,antigenImageFileNamePDP:MA5-24088_Relaxin_2_P04090-1_Rat_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.5 mg/mL

Purification

Protein A/G

Storage buffer

PBS with 5% trehalose

Contains

No Preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2609758

Product Specific Information

This antibody detects both the pro and mature forms of human Relaxin-2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) Relaxin-1 or rhRelaxin-3 is observed.

Reconstitute at 0.5 mg/mL in sterile PBS.

Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.

Target Information

Relaxin 1 (also referred to as Relaxin or RLXH1) is a peptide hormone produced by the corpora lutea of the ovary during pregnancy in many mammalian species, including human. The secretion of the hormone into the blood stream just before parturition results in a marked softening and lengthening of the pubic symphysis and a softening of the cervix, which facilitates the birth process. By inhibiting uterine contractions, Relaxin 1 may influence the timing of parturition. Like insulin, Relaxin 1 consists of two peptide chains, A and B, covalently linked by disulfide bonds. By further analogy to insulin, the two peptides are synthesized as a single-chain precursor polypeptide with the B chain at the amino-terminus. The gene that encodes the human Relaxin 1 protein maps to chromosome 9. Relaxin 2, a related protein, is selectively expressed in the ovary during pregnancy. The gene that encodes the human Relaxin 2 protein also maps to chromosome 9.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.