Thermo Fisher Scientific ERK2 Internal Monoclonal Antibody (3H9.A1.A8), HRP

Applications and Tested Dilution

Product Specifications

Available Formats

• Unconjugated
• Biotin
• DyLight 680
• DyLight 800
• FITC
• Custom conjugation available upon request

Product Specific Information

• Store vial at 4°C prior to restoration.
• For extended storage, aliquot and freeze at -20°C or below. Avoid freeze/thaw cycles.
• Centrifuge product if not clear after standing at room temperature.
• Stable for several weeks at 4°C as an undiluted liquid.
• Dilute only prior to immediate use.

Anti-ERK2 is purified from tissue culture supernatant by Protein A purification. Cross-reactivity is expected with human, mouse, and rat based on sequence identity of the peptide immunogen. This antibody does not react with the ERK1 isoform.

Target Information

MAPK1 (ERK2) is a serine/threonine kinase that acts as an important activator of p90 RSK, MSK, ELK1, and Stat3, and is involved in the MAPK pathway. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as integration points for multiple biochemical signals and are involved in various cellular processes such as proliferation, differentiation, transcription regulation, and development. Activation of this kinase requires phosphorylation by upstream kinases, after which it translocates to the nucleus to phosphorylate nuclear targets.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.