Thermo Fisher Scientific L-Selectin (CD62L) Recombinant Rat Monoclonal Antibody (MEL-14)
Thermo Fisher Scientific의 L-Selectin (CD62L) Recombinant Rat Monoclonal Antibody (MEL-14)는 마우스 CD62L을 특이적으로 인식하는 항체로, IHC, Flow Cytometry, IP, Inhibition Assay 등에 사용됩니다. 단백질 A로 정제된 액상 형태이며, 장기보관 시 -20°C에서 보관합니다.
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Applications
- Immunohistochemistry (IHC): Assay-dependent
- Flow Cytometry (Flow): Assay-dependent
- Immunoprecipitation (IP): Assay-dependent
- Inhibition Assays (IA): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rat / IgG2a, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | MEL-14 |
| Immunogen | C3H/eb mouse B lymphoma 38C-13 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_3074451 |
Product Specific Information
This antibody binds to mouse CD62L, the peripheral lymph node homing receptor. CD62L is a lectin-like cell surface protein that is rapidly down-regulated upon cell activation with phorbol 12-myristate 13-acetate.
Target Information
Human CD62L (L-Selectin) is a 74–95 kDa glycoprotein, a member of the selectin family of adhesion receptors. It comprises:
- An aminoterminal C-type lectin binding domain
- An EGF-like domain
- Two short consensus repeat (SCR) sequences homologous to complement binding proteins
- A short spacer region, transmembrane region, and cytoplasmic region
CD62L is constitutively expressed on all classes of leukocytes, including lymphocytes (except a substantial population of memory T cells), monocytes, and polymorphonuclear cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: MA5-48008_L-Selectin_CD62L_P18337-1_Rat.svg, MA5-48008_L-Selectin_CD62L_P18337-1_Rat_PDP.jpeg)
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