Thermo Fisher Scientific L-Selectin (CD62L) Chimeric Recombinant Rabbit Monoclonal Antibody (MEL-14)
Thermo Fisher의 L-Selectin (CD62L) 키메릭 재조합 토끼 단클론 항체(MEL-14)는 마우스 CD62L을 특이적으로 인식하며, IHC, Flow Cytometry, IP, Inhibition Assay에 사용 가능. HEK293 세포에서 발현된 Recombinant IgG 항체로 높은 순도와 안정성을 제공.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (IHC) | Assay-dependent |
| Flow Cytometry (Flow) | 10 µg/mL |
| Immunoprecipitation (IP) | Assay-dependent |
| Inhibition Assays (IA) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | MEL-14 |
| Immunogen | C3H/eb mouse B lymphoma 38C-13 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3074450 |
Product Specific Information
This antibody binds to mouse CD62L, the peripheral lymph node homing receptor. CD62L is a lectin-like cell surface protein that is rapidly down-regulated upon cell activation with phorbol 12-myristate 13-acetate.
Target Information
Human CD62L (L-Selectin) is a 74–95 kDa glycoprotein belonging to the selectin family of adhesion receptors.
It contains:
- Aminoterminal C-type lectin binding domain
- Epidermal growth factor-like domain
- Two short consensus repeat (SCR) sequences homologous to complement binding proteins
- Short spacer region
- Transmembrane region
- Short cytoplasmic region
CD62L is constitutively expressed on all classes of leukocytes including lymphocytes (except a substantial population of memory T cells), monocytes, and polymorphonuclear cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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