Thermo Fisher Scientific TTR Monoclonal Antibody (2E10C5)

Applications

Tested Dilution

Publications

Western Blot (WB)

1 µg/mL

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

2E10C5

Immunogen

Purified recombinant fragment of human TTR (AA: 1-147) expressed in E. Coli if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Transthyretin,uniProtId:P02766-1,ncbiNodeId:9606,antigenRange:1-147,antigenLength:147,antigenImageFileName:MA1-221_Transthyretin_P02766-1_House_mouse.svg,antigenImageFileNamePDP:MA1-221_Transthyretin_P02766-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2725592

Product Specific Information

MA1-221 detects Transthyretin protein in ELISA and Western Blot applications.

The MA1-221 immunogen is the purified recombinant fragment of human TTR (AA: 1-147) expressed in E. Coli.

Target Information

Transthyretin (TTR), generally called prealbumin, is a plasma protein that plays an important role in physiology such as a transporter of hormone thyroxine and retinal-binding protein. After produced primarily in the liver, TTR is excreted into the plasma. TTR represents a disproportionate fraction (25%) of CSF protein, prompting the suggestion that it is either selectively transported across the blood-CSF barrier or synthesized de novo within the central nervous system. Transthyretin is a constituent found to the neuritic plaques, neurofibrillary tangles, and microangiopathic lesions of senile cerebral amyloid. It has been reported that more than 40 different mutations in the TTR gene associated with amyloid deposition.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.