Thermo Fisher Scientific PTGER4 Polyclonal Antibody
Rabbit polyclonal antibody recognizing PTGER4 (EP4) receptor. Validated for IHC(P) and ICC/IF. Cross-reactive with multiple species including human, mouse, and rat. Supplied as liquid, 1 mg/mL in PBS with 0.1% sodium azide. For research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 3.6 µg/mL |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
Product Specifications
| Category | Description |
|---|---|
| Species Reactivity | Bat, Bovine, Dog, Horse, Hamster, Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 18 amino acid peptide from C-terminus of human PTGER4 / EP4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551476 |
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bat, Dog, Bovine, Horse (100%).
Target Information
The protein encoded by this gene is a member of the G-protein coupled receptor family. It is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling and mediate PGE2-induced expression of early growth response 1. It also regulates the level and stability of cyclooxygenase-2 mRNA and induces phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest involvement in neonatal circulatory adaptation, osteoporosis, and initiation of skin immune responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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