Thermo Fisher Scientific PTGER4 Polyclonal Antibody
인간 PTGER4 단백질을 인식하는 Rabbit Polyclonal 항체. IHC(P) 및 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태. 1 mg/mL 농도, PBS 버퍼 및 0.1% sodium azide 포함. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 2.5 µg/mL |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 14 amino acid peptide from N-terminal extracellular domain of human PTGER4 / EP4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551478 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- Human (100%)
- Chimpanzee, Gorilla, Marmoset (93%)
- Gibbon, Monkey (86%)
Target Information
The protein encoded by this gene is a member of the G-protein coupled receptor family and one of four receptors identified for prostaglandin E2.
This receptor can activate T-cell factor signaling and mediate PGE2-induced expression of early growth response 1.
It regulates the level and stability of cyclooxygenase-2 mRNA and leads to phosphorylation of glycogen synthase kinase-3.
Knockout studies in mice suggest involvement in neonatal circulatory adaptation, osteoporosis, and initiation of skin immune responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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