Thermo Fisher Scientific PTGER4 Polyclonal Antibody
Rabbit polyclonal antibody targeting human PTGER4 (EP4). Validated for IHC-P and ICC/IF applications. High specificity via antigen affinity purification. Supplied as liquid form in PBS with sodium azide. Suitable for research use only.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC-P) | 4–15 µg/mL |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 18 amino acid peptide from C-terminus of human PTGER4 / EP4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551477 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset (100%); Panda, Dog, Horse (83%).
Target Information
The protein encoded by this gene is a member of the G-protein coupled receptor family and serves as one of four receptors for prostaglandin E2. This receptor can activate T-cell factor signaling, mediate PGE2-induced expression of early growth response 1, regulate cyclooxygenase-2 mRNA stability, and promote phosphorylation of glycogen synthase kinase-3.
Knockout studies in mice suggest involvement in neonatal circulatory adaptation, osteoporosis, and initiation of skin immune responses.
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
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