Thermo Fisher Scientific IL34 Monoclonal Antibody (OTI4A6), TrueMAB
인간 IL-34 단백질을 인식하는 Mouse IgG2a 단클론 항체로, Western blot에 적합합니다. 동결건조 형태로 제공되며, 1 mg/mL 농도. PBS 버퍼 및 trehalose 포함, 보존제 없음. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): Tested dilution 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4A6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 77–242 of human IL34 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
IL-34 is secreted as a dimeric protein and currently belongs to no known cytokine family. It signals via the M-CSF receptor (CSF-1R/CD115), shared with M-CSF. Although IL-34 has no amino acid sequence homology to M-CSF, they exhibit similar secondary structures and overlapping functions. IL-34 promotes myeloid survival, proliferation, and differentiation, and plays a role in osteoclast formation. Expression is detected in various tissues, most abundantly in the spleen.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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