Thermo Fisher Scientific IL34 Monoclonal Antibody (OTI4F2), TrueMAB

Applications

• Western Blot (WB)

Tested Dilution: 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

IL-34 is secreted as a dimeric protein with no known cytokine family association. It signals through the M-CSF receptor (CSF-1R/CD115), which is shared with M-CSF. Although IL-34 has no amino acid sequence homology to M-CSF, they exhibit similar secondary structures and overlapping functions.
IL-34 promotes myeloid cell survival, proliferation, and differentiation, and plays a role in osteoclast formation. Expression is detected in various tissues, most abundantly in the spleen.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.