Thermo Fisher Scientific IL34 Monoclonal Antibody (OTI4F2), TrueMAB
인간 IL-34 단백질(77-242aa)에 특이적인 Mouse IgG1 단클론 항체. Western blot에 최적화되어 있으며, 동결건조 형태로 제공. 연구용으로만 사용 가능하며, 재구성 및 결합 실험에 적합.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4F2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 77–242 of human IL34 produced in E.coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
IL-34 is secreted as a dimeric protein with no known cytokine family association. It signals through the M-CSF receptor (CSF-1R/CD115), which is shared with M-CSF. Although IL-34 has no amino acid sequence homology to M-CSF, they exhibit similar secondary structures and overlapping functions.
IL-34 promotes myeloid cell survival, proliferation, and differentiation, and plays a role in osteoclast formation. Expression is detected in various tissues, most abundantly in the spleen.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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