Thermo Fisher Scientific PDE2A Polyclonal Antibody
Thermo Fisher Scientific의 PDE2A Polyclonal Antibody는 인간 PDE2A 단백질을 인식하는 토끼 유래 IgG 항체로, IHC(P)에서 1:50–1:200 희석 비율로 사용됩니다. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol 버퍼에 보존됩니다. 연구용으로만 사용 가능합니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
- Publications: References
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PDE2A. Recombinant protein control fragment (Product #RP-104153) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2645327 |
Product Specific Information
Immunogen sequence:
EHVIQHCFHY TSTVLTSTLA FQKEQKLKCE CQALLQVAKN LFTHLDDVSV LLQEIITEAR NLSNAEICSV FLLDQNELVA KVFDGGVVDD ESYEIRIPA
- Highest antigen sequence identity to orthologs:
- Mouse: 99%
- Rat: 97%
Target Information
PDE2A (phosphodiesterase 2A) is a 100 kD cyclic nucleotide phosphodiesterase (PDE) with three isoforms (PDE2A1, PDE2A2, PDE2A3) arising from a single gene via alternative splicing. PDE2A can degrade both cAMP and cGMP, showing higher efficacy for cGMP. It is expressed in various tissues, predominantly in the brain (cerebellum and neocortex). PDE2A has been linked to erectile dysfunction and regulation of fluid and inflammatory cell transport across the endothelial barrier.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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