Thermo Fisher Scientific SART1 Polyclonal Antibody
SART1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot, IHC, ICC/IF에 사용 가능. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 액상 항체로, 연구용에 적합.
- 카탈로그번호
- PA556664
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SART1. Recombinant protein control fragment (Product #RP-95144). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2646957 |
Product Specific Information
Immunogen sequence:
RRVKKIRKKE KEVVVRADDL LPLGDQTQDG DFGSRLRGRG RRRVSEVEEE KEPVPQPLPS DDTRVENMDI SDEEEGGAPP PGSPQVLEED EAELELQKQL EKG
Highest antigen sequence identity to the following orthologs:
- Mouse: 85%
- Rat: 83%
Target Information
This gene encodes two proteins:
- SART1 protein expressed in the nucleus of proliferating cells
- SART1 protein expressed in the cytosol of epithelial cancers
The SART1 protein is translated by -1 frameshifting during posttranscriptional regulation; its full-length sequence is not published yet. Both proteins are involved in the regulation of proliferation and possess tumor-rejection antigens.
The SART1 antigen can induce HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients and may be useful in specific immunotherapy or as a diagnostic tool for atopy. It is essential for recruitment of the tri-snRNP to the pre-spliceosome in spliceosome assembly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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