Thermo Fisher Scientific SOCS3 Monoclonal Antibody (SO1)
SOCS3 단백질을 표적으로 하는 Thermo Fisher Scientific의 SO1 단클론 항체로, 인간 및 마우스 시료에 반응합니다. Western blot, IHC, ICC/IF 등 다양한 응용에 적합하며, Protein A로 정제된 액상 형태입니다. 4°C 보관, 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Dilution: Assay-dependent
- View 1 publication
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Dilution: —
- View 1 publication
Immunocytochemistry (ICC/IF)
- Dilution: Assay-dependent
- View publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Mouse |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SO1 |
| Immunogen | Full-length SOCS3 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1087394 |
Product Specific Information
This antibody reacts with SOCS3, an intracellular cytokine signaling inhibitor.
Western Blot: Reducing conditions.
Target Information
Cytokine receptor signaling is negatively regulated by the SOCS (Suppressor of Cytokine Signaling) family, which includes SOCS-1 through SOCS-7 and CIS. These proteins contain an N-terminal variable region, a central SH2 domain, and a C-terminal SOCS box motif. SOCS proteins function as part of a negative feedback loop regulating cytokine signal transduction via STAT-induced transcription. SOCS gene transcription is rapidly induced in response to cytokines, and each SOCS member inhibits signaling through distinct mechanisms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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